Term Information [More information on nitric-oxide synthase activity]

Accession
GO:0004517
Name
nitric-oxide synthase activity
Ontology
molecular_function
Synonyms
L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) activity, NADPH-diaphorase activity, NO synthase activity, nitric oxide synthase activity, nitric oxide synthetase activity, nitric-oxide synthetase activity, endothelium-derived relaxation factor-forming enzyme activity, endothelium-derived relaxing factor synthase activity
Definition
Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+. Source: EC:1.14.13.39
Comment
None
History
See term history for GO:0004517 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0004517 from QuickGO

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Ancestors of nitric-oxide synthase activity (GO:0004517)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nitric-oxide synthase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
nitric-oxide synthase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
nitric-oxide synthase activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
nitric-oxide synthase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
nitric-oxide synthase activity [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
nitric-oxide synthase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
nitric-oxide synthase activity [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
nitric-oxide synthase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity (GO:0016491)
nitric-oxide synthase activity [Inferred is_a relation] is_a (inferred) monooxygenase activity (GO:0004497)
nitric-oxide synthase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
nitric-oxide synthase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709)
Children of nitric-oxide synthase activity (GO:0004517)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of nitric-oxide synthase activity (GO:0051001) [negatively_regulates relation] negatively_regulates  nitric-oxide synthase activity
nitric-oxide synthase complex (GO:1903958) [capable_of relation] capable_of  nitric-oxide synthase activity
nitric-oxide synthase inhibitor activity (GO:0036487) [negatively_regulates relation] negatively_regulates  nitric-oxide synthase activity
nitric-oxide synthase regulator activity (GO:0030235) [regulates relation] regulates  nitric-oxide synthase activity
positive regulation of nitric-oxide synthase activity (GO:0051000) [positively_regulates relation] positively_regulates  nitric-oxide synthase activity
regulation of nitric-oxide synthase activity (GO:0050999) [regulates relation] regulates  nitric-oxide synthase activity