Term Information [More information on monophenol monooxygenase activity]

Accession
GO:0004503
Name
monophenol monooxygenase activity
Ontology
molecular_function
Synonyms
L-tyrosine monooxygenase activity, N-acetyl-6-hydroxytryptophan oxidase activity, monophenol dihydroxyphenylalanine:oxygen oxidoreductase activity, monophenol monooxidase activity, monophenol oxidase activity, monophenol oxygenase, monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase activity, monophenol,L-dopa:oxygen oxidoreductase activity, monophenolase activity, polyaromatic oxidase activity, polyphenolase activity, tyrosinase activity, tyrosine-dopa oxidase activity, catecholase, chlorogenic acid oxidase activity, chlorogenic oxidase activity, cresolase activity, dopa oxidase, o-diphenol oxidase activity, o-diphenol oxidoreductase, o-diphenol:O2 oxidoreductase activity, o-diphenol:oxygen oxidoreductase, prophenol oxidase activity, prophenoloxidase activity, phenol oxidase activity, phenolase activity, pyrocatechol oxidase
Definition
Catalysis of the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O. Source: PMID:4965136, GOC:sart, EC:1.14.18.1, GOC:bf
Comment
In mammals, L-DOPA can act as a cofactor for the catalyzed reaction; therefore in some resources L-DOPA is shown on both sides of the reaction. GO:0004503 describes the monooxygenation of the monophenol, L-tyrosine. For oxidation of diphenols (including L-DOPA and dopamine), consider instead the term 'catechol oxidase activity ; GO:0004097' and its children.
History
See term history for GO:0004503 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0004503 from QuickGO

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Ancestors of monophenol monooxygenase activity (GO:0004503)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
monophenol monooxygenase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
monophenol monooxygenase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
monophenol monooxygenase activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
monophenol monooxygenase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
monophenol monooxygenase activity [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
monophenol monooxygenase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
monophenol monooxygenase activity [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
monophenol monooxygenase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity (GO:0016491)
monophenol monooxygenase activity [Inferred is_a relation] is_a (inferred) monooxygenase activity (GO:0004497)
monophenol monooxygenase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
monophenol monooxygenase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen (GO:0016716)
Children of monophenol monooxygenase activity (GO:0004503)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of monophenol monooxygenase activity (GO:0032772) [negatively_regulates relation] negatively_regulates  monophenol monooxygenase activity
positive regulation of monophenol monooxygenase activity (GO:0032773) [positively_regulates relation] positively_regulates  monophenol monooxygenase activity
regulation of monophenol monooxygenase activity (GO:0032771) [regulates relation] regulates  monophenol monooxygenase activity