Term Information [More information on malate dehydrogenase (decarboxylating) (NADP+) activity]

Accession
GO:0004473
Name
malate dehydrogenase (decarboxylating) (NADP+) activity
Ontology
molecular_function
Synonyms
(S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating), L-malate:NADP oxidoreductase activity, NADP-malic enzyme activity, NADP-specific malate dehydrogenase activity, malate dehydrogenase (NADP, decarboxylating), malate dehydrogenase (decarboxylating, NADP), 'malic' enzyme, NADP-linked decarboxylating malic enzyme, NADP-specific malic enzyme
Definition
Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+. Source: EC:1.1.1.40
Comment
For decarboxylation of oxaloacetate (the second substrate listed in EC:1.1.1.40), see 'oxaloacetate decarboxylase activity ; GO:0008948'.
History
See term history for GO:0004473 at QuickGO
Subset
gosubset_prok
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
Contact the GO Helpdesk if you find mistakes or have concerns about the data you find here.
Contacting server...
View this term in QuickGO.

Graph of GO:0004473 from QuickGO

Additional external viewing options
Additional internal viewing options
Ancestors of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:0004473)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
malate dehydrogenase (decarboxylating) (NADP+) activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
malate dehydrogenase (decarboxylating) (NADP+) activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
malate dehydrogenase (decarboxylating) (NADP+) activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
malate dehydrogenase (decarboxylating) (NADP+) activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
malate dehydrogenase (decarboxylating) (NADP+) activity [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
malate dehydrogenase (decarboxylating) (NADP+) activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
malate dehydrogenase (decarboxylating) (NADP+) activity [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
malate dehydrogenase (decarboxylating) (NADP+) activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity (GO:0016491)
malate dehydrogenase (decarboxylating) (NADP+) activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity, acting on CH-OH group of donors (GO:0016614)
malate dehydrogenase (decarboxylating) (NADP+) activity [Inferred is_a relation] is_a (inferred) malate dehydrogenase activity (GO:0016615)
malate dehydrogenase (decarboxylating) (NADP+) activity [is_a relation] is_a  malic enzyme activity (GO:0004470)
malate dehydrogenase (decarboxylating) (NADP+) activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
Children of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:0004473)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:1903219) [negatively_regulates relation] negatively_regulates  malate dehydrogenase (decarboxylating) (NADP+) activity
positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:1903220) [positively_regulates relation] positively_regulates  malate dehydrogenase (decarboxylating) (NADP+) activity
regulation of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:1903218) [regulates relation] regulates  malate dehydrogenase (decarboxylating) (NADP+) activity
EC
1.1.1.40
KEGG
R00216
MetaCyc
MALIC-NADP-RXN
RHEA
18256