Term Information [More information on malate dehydrogenase (decarboxylating) (NAD+) activity]

Accession
GO:0004471
Name
malate dehydrogenase (decarboxylating) (NAD+) activity
Ontology
molecular_function
Synonyms
alt. id: GO:0016619, GO:0004472
(S)-malate:NAD+ oxidoreductase (decarboxylating), (S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating), malate dehydrogenase (decarboxylating) activity, malate dehydrogenase (oxaloacetate-decarboxylating) activity, 'malic' enzyme, NAD-linked malic enzyme, NAD-specific malic enzyme, NAD-malic enzyme activity
Definition
Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+. Source: EC:1.1.1.38, EC:1.1.1.39
Comment
For decarboxylation of oxaloacetate (the second substrate listed in EC:1.1.1.38), see 'oxaloacetate decarboxylase activity ; GO:0008948'.
History
See term history for GO:0004471 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0004471 from QuickGO

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Ancestors of malate dehydrogenase (decarboxylating) (NAD+) activity (GO:0004471)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
malate dehydrogenase (decarboxylating) (NAD+) activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
malate dehydrogenase (decarboxylating) (NAD+) activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
malate dehydrogenase (decarboxylating) (NAD+) activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
malate dehydrogenase (decarboxylating) (NAD+) activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
malate dehydrogenase (decarboxylating) (NAD+) activity [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
malate dehydrogenase (decarboxylating) (NAD+) activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
malate dehydrogenase (decarboxylating) (NAD+) activity [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
malate dehydrogenase (decarboxylating) (NAD+) activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity (GO:0016491)
malate dehydrogenase (decarboxylating) (NAD+) activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity, acting on CH-OH group of donors (GO:0016614)
malate dehydrogenase (decarboxylating) (NAD+) activity [Inferred is_a relation] is_a (inferred) malate dehydrogenase activity (GO:0016615)
malate dehydrogenase (decarboxylating) (NAD+) activity [is_a relation] is_a  malic enzyme activity (GO:0004470)
malate dehydrogenase (decarboxylating) (NAD+) activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)

This term has no children.

EC
1.1.1.38
1.1.1.39
KEGG
R00214
MetaCyc
1.1.1.39-RXN
MALIC-NAD-RXN
RHEA
12656