Term Information [More information on leukotriene-C4 synthase activity]

Accession
GO:0004464
Name
leukotriene-C4 synthase activity
Ontology
molecular_function
Synonyms
(7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening), (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming), LTC(4) synthase activity, LTC(4) synthetase activity, LTC4 synthase activity, LTC4 synthetase activity, leukotriene A(4):glutathione S-leukotrienyltransferase activity, leukotriene A4:glutathione S-leukotrienyltransferase activity, leukotriene C(4) synthetase activity, leukotriene C4 synthetase activity, leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)
Definition
Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4). Source: RHEA:17620, EC:4.4.1.20
Comment
Note that this function was EC:2.5.1.37.
History
See term history for GO:0004464 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0004464 from QuickGO

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Ancestors of leukotriene-C4 synthase activity (GO:0004464)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
leukotriene-C4 synthase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
leukotriene-C4 synthase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
leukotriene-C4 synthase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
leukotriene-C4 synthase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
leukotriene-C4 synthase activity [Inferred is_a relation] is_a (inferred) lyase activity (GO:0016829)
leukotriene-C4 synthase activity [is_a relation] is_a  carbon-sulfur lyase activity (GO:0016846)

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