Term Information [More information on hydroxymethylglutaryl-CoA synthase activity]

Accession
GO:0004421
Name
hydroxymethylglutaryl-CoA synthase activity
Ontology
molecular_function
Synonyms
(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating), (s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity, 3-hydroxy-3-methylglutaryl CoA synthetase activity, 3-hydroxy-3-methylglutaryl coenzyme A synthase activity, 3-hydroxy-3-methylglutaryl coenzyme A synthetase activity, 3-hydroxy-3-methylglutaryl-CoA synthase activity, 3-hydroxy-3-methylglutaryl-coenzyme A synthase activity, HMG-CoA synthase activity, acetoacetyl coenzyme A transacetase activity, acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming), beta-hydroxy-beta-methylglutaryl-CoA synthase activity, hydroxymethylglutaryl coenzyme A synthase activity, hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity, hydroxymethylglutaryl coenzyme A-condensing enzyme
Definition
Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+). Source: RHEA:10191, EC:2.3.3.10
Comment
Note that this function was formerly EC:4.1.3.5.
History
See term history for GO:0004421 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0004421 from QuickGO

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Ancestors of hydroxymethylglutaryl-CoA synthase activity (GO:0004421)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
hydroxymethylglutaryl-CoA synthase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
hydroxymethylglutaryl-CoA synthase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
hydroxymethylglutaryl-CoA synthase activity [Inferred is_a relation] is_a (inferred) transferase activity (GO:0016740)
hydroxymethylglutaryl-CoA synthase activity [Inferred is_a relation] is_a (inferred) transferase activity, transferring acyl groups (GO:0016746)
hydroxymethylglutaryl-CoA synthase activity [is_a relation] is_a  transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer (GO:0046912)

This term has no children.