Term Information [More information on hydroxymethylglutaryl-CoA reductase (NADPH) activity]

Accession
GO:0004420
Name
hydroxymethylglutaryl-CoA reductase (NADPH) activity
Ontology
molecular_function
Synonyms
3-hydroxy-3-methylglutaryl-coenzyme A reductase activity, HMG-CoA reductase activity
Definition
Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH. Source: RHEA:15992, EC:1.1.1.34
Comment
None
History
See term history for GO:0004420 at QuickGO
Subset
gosubset_prok
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
Contact the GO Helpdesk if you find mistakes or have concerns about the data you find here.
Contacting server...
View this term in QuickGO.

Graph of GO:0004420 from QuickGO

Additional external viewing options
Additional internal viewing options
Ancestors of hydroxymethylglutaryl-CoA reductase (NADPH) activity (GO:0004420)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
hydroxymethylglutaryl-CoA reductase (NADPH) activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
hydroxymethylglutaryl-CoA reductase (NADPH) activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
hydroxymethylglutaryl-CoA reductase (NADPH) activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
hydroxymethylglutaryl-CoA reductase (NADPH) activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
hydroxymethylglutaryl-CoA reductase (NADPH) activity [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
hydroxymethylglutaryl-CoA reductase (NADPH) activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
hydroxymethylglutaryl-CoA reductase (NADPH) activity [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
hydroxymethylglutaryl-CoA reductase (NADPH) activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity (GO:0016491)
hydroxymethylglutaryl-CoA reductase (NADPH) activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity, acting on CH-OH group of donors (GO:0016614)
hydroxymethylglutaryl-CoA reductase (NADPH) activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
Children of hydroxymethylglutaryl-CoA reductase (NADPH) activity (GO:0004420)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity (GO:2001216) [negatively_regulates relation] negatively_regulates  hydroxymethylglutaryl-CoA reductase (NADPH) activity
positive regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity (GO:1900490) [positively_regulates relation] positively_regulates  hydroxymethylglutaryl-CoA reductase (NADPH) activity
regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity (GO:2001215) [regulates relation] regulates  hydroxymethylglutaryl-CoA reductase (NADPH) activity