Term Information [More information on helicase activity]

Accession
GO:0004386
Name
helicase activity
Ontology
molecular_function
Synonyms
None
Definition
Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA or RNA helix. Source: GOC:mah, ISBN:0198506732
Comment
Note that most helicases catalyze processive duplex unwinding.
History
See term history for GO:0004386 at QuickGO
Subset
gosubset_prok
goslim_generic
goslim_pir
goslim_candida
goslim_aspergillus
goslim_chembl
goslim_metagenomics
goslim_yeast
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
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Graph of GO:0004386 from QuickGO

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Ancestors of helicase activity (GO:0004386)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
helicase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
helicase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
helicase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
helicase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
helicase activity [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
helicase activity [Inferred is_a relation] is_a (inferred) hydrolase activity, acting on acid anhydrides (GO:0016817)
helicase activity [Inferred is_a relation] is_a (inferred) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818)
helicase activity [Inferred is_a relation] is_a (inferred) pyrophosphatase activity (GO:0016462)
helicase activity [is_a relation] is_a  nucleoside-triphosphatase activity (GO:0017111)
Children of helicase activity (GO:0004386)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA helicase activity (GO:0003678) [is_a relation] is_a  helicase activity
DNA/RNA helicase activity (GO:0033677) [is_a relation] is_a  helicase activity
negative regulation of helicase activity (GO:0051097) [negatively_regulates relation] negatively_regulates  helicase activity
positive regulation of helicase activity (GO:0051096) [positively_regulates relation] positively_regulates  helicase activity
purine NTP-dependent helicase activity (GO:0070035) [is_a relation] is_a  helicase activity
regulation of helicase activity (GO:0051095) [regulates relation] regulates  helicase activity
RNA helicase activity (GO:0003724) [is_a relation] is_a  helicase activity