Term Information [More information on glutathione-disulfide reductase activity]

Accession
GO:0004362
Name
glutathione-disulfide reductase activity
Ontology
molecular_function
Synonyms
GSH reductase activity, GSSG reductase activity, NADPH-GSSG reductase activity, NADPH-glutathione reductase activity, NADPH:oxidized-glutathione oxidoreductase activity, glutathione S-reductase activity, glutathione reductase (NADPH) activity, glutathione reductase activity, glutathione-disulphide reductase activity, glutathione:NADP+ oxidoreductase activity, oxidized glutathione reduction
Definition
Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+. Source: EC:1.8.1.7, ISBN:0198506732
Comment
Note that this function was formerly EC:1.6.4.2.
History
See term history for GO:0004362 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0004362 from QuickGO

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Ancestors of glutathione-disulfide reductase activity (GO:0004362)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
glutathione-disulfide reductase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
glutathione-disulfide reductase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
glutathione-disulfide reductase activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
glutathione-disulfide reductase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
glutathione-disulfide reductase activity [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
glutathione-disulfide reductase activity [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
glutathione-disulfide reductase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
glutathione-disulfide reductase activity [Inferred occurs_in relation] occurs_in (inferred) material anatomical entity (CARO:0000006)
glutathione-disulfide reductase activity [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
glutathione-disulfide reductase activity [Inferred part_of relation] part_of (inferred) response to chemical (GO:0042221)
glutathione-disulfide reductase activity [Inferred occurs_in relation] occurs_in (inferred) anatomical structure (CARO:0000003)
glutathione-disulfide reductase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity (GO:0016491)
glutathione-disulfide reductase activity [Inferred part_of relation] part_of (inferred) response to toxic substance (GO:0009636)
glutathione-disulfide reductase activity [Inferred occurs_in relation] occurs_in (inferred) cell (CL:0000000)
glutathione-disulfide reductase activity [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
glutathione-disulfide reductase activity [Inferred part_of relation] part_of (inferred) detoxification (GO:0098754)
glutathione-disulfide reductase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity, acting on a sulfur group of donors (GO:0016667)
glutathione-disulfide reductase activity [Inferred part_of relation] part_of (inferred) cellular detoxification (GO:1990748)
glutathione-disulfide reductase activity [Inferred is_a relation] is_a (inferred) disulfide oxidoreductase activity (GO:0015036)
glutathione-disulfide reductase activity [Inferred part_of relation] part_of (inferred) cellular oxidant detoxification (GO:0098869)
glutathione-disulfide reductase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity, acting on NAD(P)H (GO:0016651)
glutathione-disulfide reductase activity [Inferred is_a relation] is_a (inferred) peptide disulfide oxidoreductase activity (GO:0015037)
glutathione-disulfide reductase activity [is_a relation] is_a  antioxidant activity (GO:0016209)
glutathione-disulfide reductase activity [is_a relation] is_a  glutathione disulfide oxidoreductase activity (GO:0015038)
glutathione-disulfide reductase activity [is_a relation] is_a  oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor (GO:0016668)

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