Term Information [More information on glucosylceramidase activity]

Accession
GO:0004348
Name
glucosylceramidase activity
Ontology
molecular_function
Synonyms
D-glucosyl-N-acylsphingosine glucohydrolase activity, GlcCer-beta-glucosidase activity, acid beta-glucosidase activity, beta-D-glucocerebrosidase activity, beta-glucocerebrosidase activity, beta-glucosylceramidase activity, ceramide glucosidase activity, glucocerebrosidase activity, glucosphingosine glucosylhydrolase activity, glucosylcerebrosidase activity, glucosylsphingosine beta-D-glucosidase activity, glucosylsphingosine beta-glucosidase activity, psychosine hydrolase activity
Definition
Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine. Source: EC:3.2.1.45
Comment
None
History
See term history for GO:0004348 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0004348 from QuickGO

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Ancestors of glucosylceramidase activity (GO:0004348)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
glucosylceramidase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
glucosylceramidase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
glucosylceramidase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
glucosylceramidase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
glucosylceramidase activity [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
glucosylceramidase activity [Inferred is_a relation] is_a (inferred) hydrolase activity, acting on glycosyl bonds (GO:0016798)
glucosylceramidase activity [is_a relation] is_a  hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553)
Children of glucosylceramidase activity (GO:0004348)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of glucosylceramidase activity (GO:1905124) [negatively_regulates relation] negatively_regulates  glucosylceramidase activity
positive regulation of glucosylceramidase activity (GO:1905125) [positively_regulates relation] positively_regulates  glucosylceramidase activity
regulation of glucosylceramidase activity (GO:1905123) [regulates relation] regulates  glucosylceramidase activity