Term Information [More information on cysteine-type endopeptidase activity]

Accession
GO:0004197
Name
cysteine-type endopeptidase activity
Ontology
molecular_function
Synonyms
thiol endopeptidase activity, caspase activity, lysosomal cysteine-type endopeptidase, metacaspase activity
Definition
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. Source: http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE, GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE
Comment
None
History
See term history for GO:0004197 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0004197 from QuickGO

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Ancestors of cysteine-type endopeptidase activity (GO:0004197)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cysteine-type endopeptidase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
cysteine-type endopeptidase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
cysteine-type endopeptidase activity [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
cysteine-type endopeptidase activity [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
cysteine-type endopeptidase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
cysteine-type endopeptidase activity [Inferred part_of relation] part_of (inferred) primary metabolic process (GO:0044238)
cysteine-type endopeptidase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
cysteine-type endopeptidase activity [Inferred part_of relation] part_of (inferred) protein metabolic process (GO:0019538)
cysteine-type endopeptidase activity [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
cysteine-type endopeptidase activity [Inferred part_of relation] part_of (inferred) proteolysis (GO:0006508)
cysteine-type endopeptidase activity [Inferred is_a relation] is_a (inferred) peptidase activity (GO:0008233)
cysteine-type endopeptidase activity [Inferred is_a relation] is_a (inferred) peptidase activity, acting on L-amino acid peptides (GO:0070011)
cysteine-type endopeptidase activity [is_a relation] is_a  cysteine-type peptidase activity (GO:0008234)
cysteine-type endopeptidase activity [is_a relation] is_a  endopeptidase activity (GO:0004175)
Children of cysteine-type endopeptidase activity (GO:0004197)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
calcium-dependent cysteine-type endopeptidase activity (GO:0004198) [is_a relation] is_a  cysteine-type endopeptidase activity
caspase complex (GO:0008303) [capable_of relation] capable_of  cysteine-type endopeptidase activity
cysteine-type endopeptidase activity involved in apoptotic process (GO:0097153) [is_a relation] is_a  cysteine-type endopeptidase activity
cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:0097199) [is_a relation] is_a  cysteine-type endopeptidase activity
cysteine-type endopeptidase activity involved in execution phase of apoptosis (GO:0097200) [is_a relation] is_a  cysteine-type endopeptidase activity
cysteine-type endopeptidase activity involved in plant-type hypersensitive response (GO:0097299) [is_a relation] is_a  cysteine-type endopeptidase activity
negative regulation of cysteine-type endopeptidase activity (GO:2000117) [negatively_regulates relation] negatively_regulates  cysteine-type endopeptidase activity
positive regulation of cysteine-type endopeptidase activity (GO:2001056) [positively_regulates relation] positively_regulates  cysteine-type endopeptidase activity
regulation of cysteine-type endopeptidase activity (GO:2000116) [regulates relation] regulates  cysteine-type endopeptidase activity
ubiquitin-like protein-specific endopeptidase activity (GO:0070137) [is_a relation] is_a  cysteine-type endopeptidase activity
EC
3.4.22
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