Term Information [More information on aspartic-type endopeptidase activity]

Accession
GO:0004190
Name
aspartic-type endopeptidase activity
Ontology
molecular_function
Synonyms
aspartic endopeptidase activity, aspartate protease activity, aspartic protease activity, aspartyl protease activity, carboxyl protease activity
Definition
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. Source: ISBN:0198506732
Comment
None
History
See term history for GO:0004190 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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View this term in QuickGO.

Graph of GO:0004190 from QuickGO

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Ancestors of aspartic-type endopeptidase activity (GO:0004190)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aspartic-type endopeptidase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
aspartic-type endopeptidase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
aspartic-type endopeptidase activity [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
aspartic-type endopeptidase activity [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
aspartic-type endopeptidase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
aspartic-type endopeptidase activity [Inferred part_of relation] part_of (inferred) primary metabolic process (GO:0044238)
aspartic-type endopeptidase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
aspartic-type endopeptidase activity [Inferred part_of relation] part_of (inferred) protein metabolic process (GO:0019538)
aspartic-type endopeptidase activity [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
aspartic-type endopeptidase activity [Inferred part_of relation] part_of (inferred) proteolysis (GO:0006508)
aspartic-type endopeptidase activity [Inferred is_a relation] is_a (inferred) peptidase activity (GO:0008233)
aspartic-type endopeptidase activity [Inferred is_a relation] is_a (inferred) peptidase activity, acting on L-amino acid peptides (GO:0070011)
aspartic-type endopeptidase activity [is_a relation] is_a  aspartic-type peptidase activity (GO:0070001)
aspartic-type endopeptidase activity [is_a relation] is_a  endopeptidase activity (GO:0004175)
Children of aspartic-type endopeptidase activity (GO:0004190)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aspartic endopeptidase activity, intramembrane cleaving (GO:0042500) [is_a relation] is_a  aspartic-type endopeptidase activity
aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process (GO:1902944) [is_a relation] is_a  aspartic-type endopeptidase activity
aspartic-type endopeptidase inhibitor activity (GO:0019828) [negatively_regulates relation] negatively_regulates  aspartic-type endopeptidase activity