Term Information [More information on cytochrome-c oxidase activity]

Accession
GO:0004129
Name
cytochrome-c oxidase activity
Ontology
molecular_function
Synonyms
NADH cytochrome c oxidase, cytochrome c oxidase activity, complex IV (mitochondrial electron transport) activity, cytochrome oxidase activity, warburg's respiratory enzyme activity, aa3-type cytochrome c oxidase, ba3-type cytochrome c oxidase, caa3-type cytochrome c oxidase, cbb3-type cytochrome c oxidase, cytochrome a3 activity, cytochrome aa3 activity, ferrocytochrome c oxidase, ferrocytochrome-c:oxygen oxidoreductase, indophenol oxidase, indophenolase
Definition
Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O. Source: EC:1.9.3.1
Comment
The reduction of O2 to water is accompanied by the extrusion of four protons from the intramitochondrial compartment.
History
See term history for GO:0004129 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0004129 from QuickGO

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Ancestors of cytochrome-c oxidase activity (GO:0004129)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) localization (GO:0051179)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) establishment of localization (GO:0051234)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) single-organism localization (GO:1902578)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) transport (GO:0006810)
cytochrome-c oxidase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) single-organism transport (GO:0044765)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) transmembrane transport (GO:0055085)
cytochrome-c oxidase activity [Inferred is_a relation] is_a (inferred) transporter activity (GO:0005215)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) ion transport (GO:0006811)
cytochrome-c oxidase activity [Inferred is_a relation] is_a (inferred) substrate-specific transporter activity (GO:0022892)
cytochrome-c oxidase activity [Inferred is_a relation] is_a (inferred) transmembrane transporter activity (GO:0022857)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) cation transport (GO:0006812)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) ion transmembrane transport (GO:0034220)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
cytochrome-c oxidase activity [Inferred is_a relation] is_a (inferred) substrate-specific transmembrane transporter activity (GO:0022891)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) cation transmembrane transport (GO:0098655)
cytochrome-c oxidase activity [Inferred is_a relation] is_a (inferred) ion transmembrane transporter activity (GO:0015075)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
cytochrome-c oxidase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
cytochrome-c oxidase activity [Inferred is_a relation] is_a (inferred) cation transmembrane transporter activity (GO:0008324)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) hydrogen transport (GO:0006818)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) inorganic ion transmembrane transport (GO:0098660)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) monovalent inorganic cation transport (GO:0015672)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) inorganic cation transmembrane transport (GO:0098662)
cytochrome-c oxidase activity [Inferred is_a relation] is_a (inferred) inorganic cation transmembrane transporter activity (GO:0022890)
cytochrome-c oxidase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity (GO:0016491)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) proton transport (GO:0015992)
cytochrome-c oxidase activity [Inferred part_of relation] part_of (inferred) hydrogen ion transmembrane transport (GO:1902600)
cytochrome-c oxidase activity [Inferred is_a relation] is_a (inferred) monovalent inorganic cation transmembrane transporter activity (GO:0015077)
cytochrome-c oxidase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity, acting on a heme group of donors (GO:0016675)
cytochrome-c oxidase activity [is_a relation] is_a  electron carrier activity (GO:0009055)
cytochrome-c oxidase activity [is_a relation] is_a  heme-copper terminal oxidase activity (GO:0015002)
cytochrome-c oxidase activity [is_a relation] is_a  hydrogen ion transmembrane transporter activity (GO:0015078)
cytochrome-c oxidase activity [is_a relation] is_a  oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor (GO:0016676)
Children of cytochrome-c oxidase activity (GO:0004129)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of cytochrome-c oxidase activity (GO:1904960) [positively_regulates relation] positively_regulates  cytochrome-c oxidase activity
regulation of cytochrome-c oxidase activity (GO:1904959) [regulates relation] regulates  cytochrome-c oxidase activity