Term Information [More information on aconitate hydratase activity]

Accession
GO:0003994
Name
aconitate hydratase activity
Ontology
molecular_function
Synonyms
aconitase activity, cis-aconitase activity, citrate(isocitrate) hydro-lyase (cis-aconitate-forming), citrate(isocitrate) hydro-lyase activity, citrate hydro-lyase activity
Definition
Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate. Source: GOC:pde, GOC:vw, EC:4.2.1.3
Comment
This is a process composed of two reactions represented by the terms 'GO:0052632 : citrate hydro-lyase (cis-aconitate-forming) activity' and 'GO:0052633 : isocitrate hydro-lyase (cis-aconitate-forming) activity'.
History
See term history for GO:0003994 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0003994 from QuickGO

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Ancestors of aconitate hydratase activity (GO:0003994)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aconitate hydratase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
aconitate hydratase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
aconitate hydratase activity [Inferred is_a relation] is_a (inferred) lyase activity (GO:0016829)
aconitate hydratase activity [Inferred is_a relation] is_a (inferred) carbon-oxygen lyase activity (GO:0016835)
aconitate hydratase activity [is_a relation] is_a  hydro-lyase activity (GO:0016836)
Children of aconitate hydratase activity (GO:0003994)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of aconitate hydratase activity (GO:1904233) [negatively_regulates relation] negatively_regulates  aconitate hydratase activity
positive regulation of aconitate hydratase activity (GO:1904234) [positively_regulates relation] positively_regulates  aconitate hydratase activity
regulation of aconitate hydratase activity (GO:1904232) [regulates relation] regulates  aconitate hydratase activity