Term Information [More information on DNA topoisomerase type II (ATP-hydrolyzing) activity]

Accession
GO:0003918
Name
DNA topoisomerase type II (ATP-hydrolyzing) activity
Ontology
molecular_function
Synonyms
DNA topoisomerase IV activity, deoxyribonucleic topoisomerase activity, type II DNA topoisomerase activity, DNA topoisomerase II, DNA topoisomerase type II activity, topoisomerase II, DNA topoisomerase (ATP-hydrolysing), deoxyribonucleate topoisomerase, topoisomerase
Definition
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. Source: PMID:8811192
Comment
None
History
See term history for GO:0003918 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0003918 from QuickGO

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Ancestors of DNA topoisomerase type II (ATP-hydrolyzing) activity (GO:0003918)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA topoisomerase type II (ATP-hydrolyzing) activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
DNA topoisomerase type II (ATP-hydrolyzing) activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
DNA topoisomerase type II (ATP-hydrolyzing) activity [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
DNA topoisomerase type II (ATP-hydrolyzing) activity [Inferred is_a relation] is_a (inferred) hydrolase activity, acting on acid anhydrides (GO:0016817)
DNA topoisomerase type II (ATP-hydrolyzing) activity [Inferred is_a relation] is_a (inferred) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818)
DNA topoisomerase type II (ATP-hydrolyzing) activity [Inferred is_a relation] is_a (inferred) pyrophosphatase activity (GO:0016462)
DNA topoisomerase type II (ATP-hydrolyzing) activity [Inferred is_a relation] is_a (inferred) nucleoside-triphosphatase activity (GO:0017111)
DNA topoisomerase type II (ATP-hydrolyzing) activity [Inferred is_a relation] is_a (inferred) ATPase activity (GO:0016887)
DNA topoisomerase type II (ATP-hydrolyzing) activity [Inferred is_a relation] is_a (inferred) isomerase activity (GO:0016853)
DNA topoisomerase type II (ATP-hydrolyzing) activity [Inferred is_a relation] is_a (inferred) ATPase activity, coupled (GO:0042623)
DNA topoisomerase type II (ATP-hydrolyzing) activity [Inferred is_a relation] is_a (inferred) DNA topoisomerase activity (GO:0003916)
DNA topoisomerase type II (ATP-hydrolyzing) activity [is_a relation] is_a  DNA topoisomerase II activity (GO:0061505)
DNA topoisomerase type II (ATP-hydrolyzing) activity [is_a relation] is_a  DNA-dependent ATPase activity (GO:0008094)
Children of DNA topoisomerase type II (ATP-hydrolyzing) activity (GO:0003918)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA supercoiling activity (GO:0034335) [is_a relation] is_a  DNA topoisomerase type II (ATP-hydrolyzing) activity
DNA topoisomerase (ATP-hydrolyzing) activator activity (GO:0072587) [positively_regulates relation] positively_regulates  DNA topoisomerase type II (ATP-hydrolyzing) activity
DNA topoisomerase (ATP-hydrolyzing) inhibitor activity (GO:0008657) [negatively_regulates relation] negatively_regulates  DNA topoisomerase type II (ATP-hydrolyzing) activity
DNA topoisomerase (ATP-hydrolyzing) regulator activity (GO:0072586) [regulates relation] regulates  DNA topoisomerase type II (ATP-hydrolyzing) activity
negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity (GO:2000372) [negatively_regulates relation] negatively_regulates  DNA topoisomerase type II (ATP-hydrolyzing) activity
positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity (GO:2000373) [positively_regulates relation] positively_regulates  DNA topoisomerase type II (ATP-hydrolyzing) activity
regulation of DNA topoisomerase (ATP-hydrolyzing) activity (GO:2000371) [regulates relation] regulates  DNA topoisomerase type II (ATP-hydrolyzing) activity