Term Information [More information on DNA topoisomerase type I activity]

Accession
GO:0003917
Name
DNA topoisomerase type I activity
Ontology
molecular_function
Synonyms
type I DNA topoisomerase activity, type I topoisomerase activity, nicking-closing enzyme activity, omega-protein activity, relaxing enzyme activity, swivelase activity, untwisting enzyme activity, DNA topoisomerase I activity, deoxyribonucleate topoisomerase, topoisomerase
Definition
Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle. Source: PMID:8811192
Comment
Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity.
History
See term history for GO:0003917 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0003917 from QuickGO

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Ancestors of DNA topoisomerase type I activity (GO:0003917)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA topoisomerase type I activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
DNA topoisomerase type I activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
DNA topoisomerase type I activity [Inferred is_a relation] is_a (inferred) isomerase activity (GO:0016853)
DNA topoisomerase type I activity [is_a relation] is_a  DNA topoisomerase activity (GO:0003916)

This term has no children.

EC
5.99.1.2
MetaCyc
5.99.1.2-RXN