Term Information [More information on DNA-(apurinic or apyrimidinic site) lyase activity]

Accession
GO:0003906
Name
DNA-(apurinic or apyrimidinic site) lyase activity
Ontology
molecular_function
Synonyms
AP lyase activity, AP site-DNA 5'-phosphomonoester-lyase activity, DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity, deoxyribonuclease (apurinic or apyrimidinic) activity, endodeoxyribonuclease (apurinic or apyrimidinic) activity, E. coli endonuclease III, X-ray endonuclease III, endonuclease VIII activity, AP endonuclease class I activity, E. coli endonuclease III activity, Micrococcus luteus UV endonuclease activity, Phage-T(4) UV endonuclease activity, Phage-T4 UV endonuclease activity, micrococcus luteus UV endonuclease, phage-T4 UV endonuclease
Definition
Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. Source: EC:4.2.99.18
Comment
None
History
See term history for GO:0003906 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0003906 from QuickGO

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Ancestors of DNA-(apurinic or apyrimidinic site) lyase activity (GO:0003906)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) cellular metabolic process (GO:0044237)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) nitrogen compound metabolic process (GO:0006807)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) cellular aromatic compound metabolic process (GO:0006725)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) cellular nitrogen compound metabolic process (GO:0034641)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) heterocycle metabolic process (GO:0046483)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) organic cyclic compound metabolic process (GO:1901360)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) primary metabolic process (GO:0044238)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) nucleobase-containing compound metabolic process (GO:0006139)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) nucleic acid metabolic process (GO:0090304)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) cellular macromolecule metabolic process (GO:0044260)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred is_a relation] is_a (inferred) hydrolase activity, acting on ester bonds (GO:0016788)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) nucleic acid phosphodiester bond hydrolysis (GO:0090305)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred part_of relation] part_of (inferred) DNA metabolic process (GO:0006259)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred is_a relation] is_a (inferred) nuclease activity (GO:0004518)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred is_a relation] is_a (inferred) deoxyribonuclease activity (GO:0004536)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred is_a relation] is_a (inferred) endonuclease activity (GO:0004519)
DNA-(apurinic or apyrimidinic site) lyase activity [Inferred is_a relation] is_a (inferred) lyase activity (GO:0016829)
DNA-(apurinic or apyrimidinic site) lyase activity [is_a relation] is_a  carbon-oxygen lyase activity (GO:0016835)
DNA-(apurinic or apyrimidinic site) lyase activity [is_a relation] is_a  endodeoxyribonuclease activity (GO:0004520)
Children of DNA-(apurinic or apyrimidinic site) lyase activity (GO:0003906)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
oxidized purine nucleobase lesion DNA N-glycosylase activity (GO:0008534) [is_a relation] is_a  DNA-(apurinic or apyrimidinic site) lyase activity
oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity (GO:0000703) [is_a relation] is_a  DNA-(apurinic or apyrimidinic site) lyase activity
pyrimidine dimer DNA N-glycosylase activity (GO:0000704) [is_a relation] is_a  DNA-(apurinic or apyrimidinic site) lyase activity