Term Information [More information on alkylbase DNA N-glycosylase activity]

Accession
GO:0003905
Name
alkylbase DNA N-glycosylase activity
Ontology
molecular_function
Synonyms
alt. id: GO:0004036
DNA glycosidase II activity, DNA-3-methyladenine glycosidase II activity, alkylbase DNA glycosidase activity, 3-methyladenine DNA glycosylase II, AlkA, DNA-3-methyladenine glycosylase II, deoxyribonucleate 3-methyladenine glycosidase II, alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
Definition
Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site. Source: EC:3.2.2.21, PMID:9224623, PMID:10872450, GOC:elh
Comment
None
History
See term history for GO:0003905 at QuickGO
Subset
gosubset_prok
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
Contact the GO Helpdesk if you find mistakes or have concerns about the data you find here.
Contacting server...
View this term in QuickGO.

Graph of GO:0003905 from QuickGO

Additional external viewing options
Additional internal viewing options
Ancestors of alkylbase DNA N-glycosylase activity (GO:0003905)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
alkylbase DNA N-glycosylase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
alkylbase DNA N-glycosylase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
alkylbase DNA N-glycosylase activity [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
alkylbase DNA N-glycosylase activity [Inferred is_a relation] is_a (inferred) hydrolase activity, acting on glycosyl bonds (GO:0016798)
alkylbase DNA N-glycosylase activity [Inferred is_a relation] is_a (inferred) hydrolase activity, hydrolyzing N-glycosyl compounds (GO:0016799)
alkylbase DNA N-glycosylase activity [is_a relation] is_a  DNA N-glycosylase activity (GO:0019104)
Children of alkylbase DNA N-glycosylase activity (GO:0003905)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA-1,N6-ethenoadenine N-glycosylase activity (GO:0052820) [is_a relation] is_a  alkylbase DNA N-glycosylase activity
DNA-3-methylbase glycosylase activity (GO:0043733) [is_a relation] is_a  alkylbase DNA N-glycosylase activity
DNA-5-methylcytosine glycosylase activity (GO:1990053) [is_a relation] is_a  alkylbase DNA N-glycosylase activity
DNA-7-methyladenine glycosylase activity (GO:0052821) [is_a relation] is_a  alkylbase DNA N-glycosylase activity
DNA-7-methylguanine glycosylase activity (GO:0043916) [is_a relation] is_a  alkylbase DNA N-glycosylase activity
EC
3.2.2.21
MetaCyc
3.2.2.21-RXN