Term Information [More information on Factor XII activation]

Accession
GO:0002542
Name
Factor XII activation
Ontology
biological_process
Synonyms
Hageman factor activation
Definition
Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade. Source: GOC:jal, ISBN:0721601871
Comment
None
History
See term history for GO:0002542 at QuickGO
Subset
None
Community
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Graph of GO:0002542 from QuickGO

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Ancestors of Factor XII activation (GO:0002542)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) biological_process (GO:0008150)
Factor XII activation [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) metabolic process (GO:0008152)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) cellular process (GO:0009987)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) organic substance metabolic process (GO:0071704)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) cellular metabolic process (GO:0044237)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) macromolecule metabolic process (GO:0043170)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of biological process (GO:0048518)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) primary metabolic process (GO:0044238)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of metabolic process (GO:0019222)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) response to stimulus (GO:0050896)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) cellular macromolecule metabolic process (GO:0044260)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of metabolic process (GO:0009893)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) protein metabolic process (GO:0019538)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of cellular process (GO:0050794)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of macromolecule metabolic process (GO:0060255)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of primary metabolic process (GO:0080090)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of response to stimulus (GO:0048583)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) response to stress (GO:0006950)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) cellular protein metabolic process (GO:0044267)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) defense response (GO:0006952)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) gene expression (GO:0010467)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of cellular process (GO:0048522)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of macromolecule metabolic process (GO:0010604)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of cellular metabolic process (GO:0031323)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of protein metabolic process (GO:0051246)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of response to stress (GO:0080134)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) response to external stimulus (GO:0009605)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) response to wounding (GO:0009611)
Factor XII activation [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) inflammatory response (GO:0006954)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of cellular metabolic process (GO:0031325)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of protein metabolic process (GO:0051247)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of response to stimulus (GO:0048584)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) protein maturation (GO:0051604)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) proteolysis (GO:0006508)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of cellular protein metabolic process (GO:0032268)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of defense response (GO:0031347)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of gene expression (GO:0010468)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of response to external stimulus (GO:0032101)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of response to wounding (GO:1903034)
Factor XII activation [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) acute inflammatory response (GO:0002526)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of cellular protein metabolic process (GO:0032270)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of defense response (GO:0031349)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of gene expression (GO:0010628)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of response to external stimulus (GO:0032103)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of response to wounding (GO:1903036)
Factor XII activation [Inferred part_of relation] part_of (inferred) protein activation cascade (GO:0072376)
Factor XII activation [Inferred positively_regulates relation] positively_regulates (inferred) protein processing (GO:0016485)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of inflammatory response (GO:0050727)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of protein maturation (GO:1903317)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of proteolysis (GO:0030162)
Factor XII activation [Inferred part_of relation] part_of (inferred) kinin cascade (GO:0002254)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of inflammatory response (GO:0050729)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of protein maturation (GO:1903319)
Factor XII activation [Inferred is_a relation] is_a (inferred) positive regulation of proteolysis (GO:0045862)
Factor XII activation [is_a relation] is_a  regulation of acute inflammatory response (GO:0002673)
Factor XII activation [Inferred is_a relation] is_a (inferred) regulation of protein processing (GO:0070613)
Factor XII activation [positively_regulates relation] positively_regulates  activation of plasma proteins involved in acute inflammatory response (GO:0002541)
Factor XII activation [part_of relation] part_of  plasma kallikrein-kinin cascade (GO:0002353)
Factor XII activation [is_a relation] is_a  positive regulation of acute inflammatory response (GO:0002675)
Factor XII activation [is_a relation] is_a  positive regulation of protein processing (GO:0010954)

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