Term Information [More information on store-operated calcium entry]

Accession
GO:0002115
Name
store-operated calcium entry
Ontology
biological_process
Synonyms
SOCE, capacitative calcium entry, store-operated calcium import, calcium ion import
Definition
A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum. Source: PMID:11120592, GOC:hjd, PMID:17956991
Comment
SOCE is initiated by response to stiumlation of membrane receptors leading to the hydrolysis ofphosphatidylinositol bisphosphate (PIP2), inositol 1,4,5-trisphosphate (IP3) generation, and IP3-mediated calcium ion release from the endoplasmic reticulum.
History
See term history for GO:0002115 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0002115 from QuickGO

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Ancestors of store-operated calcium entry (GO:0002115)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
store-operated calcium entry [Inferred is_a relation] is_a (inferred) biological_process (GO:0008150)
store-operated calcium entry [Inferred is_a relation] is_a (inferred) localization (GO:0051179)
store-operated calcium entry [Inferred is_a relation] is_a (inferred) establishment of localization (GO:0051234)
store-operated calcium entry [Inferred is_a relation] is_a (inferred) single-organism process (GO:0044699)
store-operated calcium entry [Inferred is_a relation] is_a (inferred) single-organism localization (GO:1902578)
store-operated calcium entry [Inferred is_a relation] is_a (inferred) transport (GO:0006810)
store-operated calcium entry [Inferred is_a relation] is_a (inferred) single-organism transport (GO:0044765)
store-operated calcium entry [Inferred is_a relation] is_a (inferred) ion transport (GO:0006811)
store-operated calcium entry [Inferred is_a relation] is_a (inferred) cation transport (GO:0006812)
store-operated calcium entry [Inferred is_a relation] is_a (inferred) divalent inorganic cation transport (GO:0072511)
store-operated calcium entry [Inferred is_a relation] is_a (inferred) metal ion transport (GO:0030001)
store-operated calcium entry [Inferred is_a relation] is_a (inferred) divalent metal ion transport (GO:0070838)
store-operated calcium entry [is_a relation] is_a  calcium ion transport (GO:0006816)
Children of store-operated calcium entry (GO:0002115)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of store-operated calcium entry (GO:2001256) [regulates relation] regulates  store-operated calcium entry
None.