Term Information [More information on epithelial to mesenchymal transition]

Accession
GO:0001837
Name
epithelial to mesenchymal transition
Ontology
biological_process
Synonyms
EMT, epithelial-mesenchymal transition
Definition
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Source: GOC:dph, PMID:14701881
Comment
None
History
See term history for GO:0001837 at QuickGO
Subset
None
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
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Graph of GO:0001837 from QuickGO

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Ancestors of epithelial to mesenchymal transition (GO:0001837)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) developmental process (GO:0032502)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) multicellular organismal process (GO:0032501)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) anatomical structure development (GO:0048856)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) single-multicellular organism process (GO:0044707)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) single-organism developmental process (GO:0044767)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) multicellular organism development (GO:0007275)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
epithelial to mesenchymal transition [Inferred is_a relation] is_a (inferred) cellular component organization or biogenesis (GO:0071840)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) cellular developmental process (GO:0048869)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) system development (GO:0048731)
epithelial to mesenchymal transition [Inferred is_a relation] is_a (inferred) anatomical structure morphogenesis (GO:0009653)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) animal organ development (GO:0048513)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) cell differentiation (GO:0030154)
epithelial to mesenchymal transition [Inferred is_a relation] is_a (inferred) cellular component organization (GO:0016043)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) tissue development (GO:0009888)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) cell development (GO:0048468)
epithelial to mesenchymal transition [Inferred is_a relation] is_a (inferred) cellular component morphogenesis (GO:0032989)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) mesenchyme development (GO:0060485)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) stem cell differentiation (GO:0048863)
epithelial to mesenchymal transition [Inferred is_a relation] is_a (inferred) cell morphogenesis (GO:0000902)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) mesenchymal cell differentiation (GO:0048762)
epithelial to mesenchymal transition [Inferred part_of relation] part_of (inferred) stem cell development (GO:0048864)
epithelial to mesenchymal transition [is_a relation] is_a  cell morphogenesis involved in differentiation (GO:0000904)
epithelial to mesenchymal transition [part_of relation] part_of  mesenchymal cell development (GO:0014031)
Children of epithelial to mesenchymal transition (GO:0001837)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cardiac epithelial to mesenchymal transition (GO:0060317) [is_a relation] is_a  epithelial to mesenchymal transition
clearance of cells from fusion plate by epithelial to mesenchymal transition (GO:0060886) [is_a relation] is_a  epithelial to mesenchymal transition
epicardial cell to mesenchymal cell transition (GO:0003347) [is_a relation] is_a  epithelial to mesenchymal transition
mesodermal to mesenchymal transition involved in gastrulation (GO:0060809) [is_a relation] is_a  epithelial to mesenchymal transition
negative regulation of epithelial to mesenchymal transition (GO:0010719) [negatively_regulates relation] negatively_regulates  epithelial to mesenchymal transition
neural crest formation (GO:0014029) [is_a relation] is_a  epithelial to mesenchymal transition
positive regulation of epithelial to mesenchymal transition (GO:0010718) [positively_regulates relation] positively_regulates  epithelial to mesenchymal transition
regulation of epithelial to mesenchymal transition (GO:0010717) [regulates relation] regulates  epithelial to mesenchymal transition
None.