Term Information [More information on immunological synapse]

Accession
GO:0001772
Name
immunological synapse
Ontology
cellular_component
Synonyms
supramolecular activation cluster, c-SMAC
Definition
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction. Source: GOC:mgi_curators, PMID:11376300, PMID:11244041
Comment
None
History
See term history for GO:0001772 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0001772 from QuickGO

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Ancestors of immunological synapse (GO:0001772)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
immunological synapse [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
immunological synapse [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
immunological synapse [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
immunological synapse [Inferred part_of relation] part_of (inferred) cell periphery (GO:0071944)
immunological synapse [Inferred part_of relation] part_of (inferred) membrane (GO:0016020)
immunological synapse [Inferred is_a relation] is_a (inferred) membrane part (GO:0044425)
immunological synapse [Inferred part_of relation] part_of (inferred) plasma membrane (GO:0005886)
immunological synapse [is_a relation] is_a  plasma membrane part (GO:0044459)

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