Term Information [More information on Prp19 complex]

Accession
GO:0000974
Name
Prp19 complex
Ontology
cellular_component
Synonyms
NTC, Prp19/CDC5 complex, nineteen complex
Definition
A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p. Source: GOC:krc, PMID:16540691, PMID:19239890
Comment
None
History
See term history for GO:0000974 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0000974 from QuickGO

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Ancestors of Prp19 complex (GO:0000974)
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Prp19 complex [Inferred is_a relation] is_a (inferred) cellular_component (GO:0005575)
Prp19 complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
Prp19 complex [is_a relation] is_a  protein complex (GO:0043234)

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