Term Information [More information on mRNA splicing, via spliceosome]

Accession
GO:0000398
Name
mRNA splicing, via spliceosome
Ontology
biological_process
Synonyms
alt. id: GO:0006374, GO:0006375
nuclear mRNA splicing, via spliceosome, splicing AT-AC intron, splicing GT-AG intron, nuclear mRNA splicing via U12-type spliceosome, nuclear mRNA splicing via U2-type spliceosome, mRNA splicing, pre-mRNA splicing
Definition
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. Source: GOC:krc, ISBN:0198506732, ISBN:0879695897
Comment
Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron.
History
See term history for GO:0000398 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0000398 from QuickGO

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Ancestors of mRNA splicing, via spliceosome (GO:0000398)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mRNA splicing, via spliceosome [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) cellular process (GO:0009987)
mRNA splicing, via spliceosome [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) cellular metabolic process (GO:0044237)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) nitrogen compound metabolic process (GO:0006807)
mRNA splicing, via spliceosome [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) cellular aromatic compound metabolic process (GO:0006725)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) cellular nitrogen compound metabolic process (GO:0034641)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) heterocycle metabolic process (GO:0046483)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) organic cyclic compound metabolic process (GO:1901360)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) primary metabolic process (GO:0044238)
mRNA splicing, via spliceosome [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) nucleobase-containing compound metabolic process (GO:0006139)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) cellular macromolecule metabolic process (GO:0044260)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) nucleic acid metabolic process (GO:0090304)
mRNA splicing, via spliceosome [Inferred part_of relation] part_of (inferred) gene expression (GO:0010467)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) RNA metabolic process (GO:0016070)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) RNA processing (GO:0006396)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) RNA splicing (GO:0008380)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) mRNA metabolic process (GO:0016071)
mRNA splicing, via spliceosome [Inferred is_a relation] is_a (inferred) RNA splicing, via transesterification reactions (GO:0000375)
mRNA splicing, via spliceosome [is_a relation] is_a  mRNA processing (GO:0006397)
mRNA splicing, via spliceosome [is_a relation] is_a  RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)
Children of mRNA splicing, via spliceosome (GO:0000398)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
alternative mRNA splicing, via spliceosome (GO:0000380) [is_a relation] is_a  mRNA splicing, via spliceosome
mRNA cis splicing, via spliceosome (GO:0045292) [is_a relation] is_a  mRNA splicing, via spliceosome
mRNA trans splicing, via spliceosome (GO:0000365) [is_a relation] is_a  mRNA splicing, via spliceosome
negative regulation of mRNA splicing, via spliceosome (GO:0048025) [negatively_regulates relation] negatively_regulates  mRNA splicing, via spliceosome
positive regulation of mRNA splicing, via spliceosome (GO:0048026) [positively_regulates relation] positively_regulates  mRNA splicing, via spliceosome
regulation of mRNA splicing, via spliceosome (GO:0048024) [regulates relation] regulates  mRNA splicing, via spliceosome
spliceosomal complex assembly (GO:0000245) [part_of relation] part_of  mRNA splicing, via spliceosome
spliceosomal complex disassembly (GO:0000390) [part_of relation] part_of  mRNA splicing, via spliceosome
spliceosomal conformational changes to generate catalytic conformation (GO:0000393) [part_of relation] part_of  mRNA splicing, via spliceosome
spliceosomal snRNP assembly (GO:0000387) [part_of relation] part_of  mRNA splicing, via spliceosome