Term Information [More information on Group I intron splicing]

Accession
GO:0000372
Name
Group I intron splicing
Ontology
biological_process
Synonyms
mRNA splicing
Definition
The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize). Source: GOC:krc, PMID:11377794
Comment
Note that Group I introns are known to be found in a number of places: rRNA, mRNA, and tRNA in organelles of fungi, plants, and protists; tRNA and mRNA of bacteria and bacteriophage; rRNA of protists and fungi; and occasionally in mRNA of animal mitochondria (e.g. sea anemone).
History
See term history for GO:0000372 at QuickGO
Subset
gosubset_prok
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
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Graph of GO:0000372 from QuickGO

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Ancestors of Group I intron splicing (GO:0000372)
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Group I intron splicing [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
Group I intron splicing [Inferred is_a relation] is_a (inferred) cellular process (GO:0009987)
Group I intron splicing [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
Group I intron splicing [Inferred is_a relation] is_a (inferred) cellular metabolic process (GO:0044237)
Group I intron splicing [Inferred is_a relation] is_a (inferred) nitrogen compound metabolic process (GO:0006807)
Group I intron splicing [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
Group I intron splicing [Inferred is_a relation] is_a (inferred) cellular aromatic compound metabolic process (GO:0006725)
Group I intron splicing [Inferred is_a relation] is_a (inferred) cellular nitrogen compound metabolic process (GO:0034641)
Group I intron splicing [Inferred is_a relation] is_a (inferred) heterocycle metabolic process (GO:0046483)
Group I intron splicing [Inferred is_a relation] is_a (inferred) organic cyclic compound metabolic process (GO:1901360)
Group I intron splicing [Inferred is_a relation] is_a (inferred) primary metabolic process (GO:0044238)
Group I intron splicing [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
Group I intron splicing [Inferred is_a relation] is_a (inferred) nucleobase-containing compound metabolic process (GO:0006139)
Group I intron splicing [Inferred is_a relation] is_a (inferred) cellular macromolecule metabolic process (GO:0044260)
Group I intron splicing [Inferred is_a relation] is_a (inferred) nucleic acid metabolic process (GO:0090304)
Group I intron splicing [Inferred part_of relation] part_of (inferred) gene expression (GO:0010467)
Group I intron splicing [Inferred is_a relation] is_a (inferred) RNA metabolic process (GO:0016070)
Group I intron splicing [Inferred is_a relation] is_a (inferred) RNA processing (GO:0006396)
Group I intron splicing [Inferred is_a relation] is_a (inferred) RNA splicing (GO:0008380)
Group I intron splicing [Inferred is_a relation] is_a (inferred) RNA splicing, via transesterification reactions (GO:0000375)
Group I intron splicing [is_a relation] is_a  RNA splicing, via transesterification reactions with guanosine as nucleophile (GO:0000376)

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