Term Information [More information on THO complex]

Accession
GO:0000347
Name
THO complex
Ontology
cellular_component
Synonyms
None
Definition
The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits. Source: GOC:krc, PMID:11060033, PMID:11979277, PMID:16983072
Comment
None
History
See term history for GO:0000347 at QuickGO
Subset
goslim_pir
Community
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Feedback
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Graph of GO:0000347 from QuickGO

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Ancestors of THO complex (GO:0000347)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
THO complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
THO complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
THO complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
THO complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
THO complex [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
THO complex [Inferred part_of relation] part_of (inferred) organelle (GO:0043226)
THO complex [Inferred part_of relation] part_of (inferred) intracellular organelle (GO:0043229)
THO complex [Inferred part_of relation] part_of (inferred) membrane-bounded organelle (GO:0043227)
THO complex [Inferred part_of relation] part_of (inferred) intracellular membrane-bounded organelle (GO:0043231)
THO complex [Inferred is_a relation] is_a (inferred) organelle part (GO:0044422)
THO complex [Inferred is_a relation] is_a (inferred) intracellular organelle part (GO:0044446)
THO complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
THO complex [Inferred part_of relation] part_of (inferred) nucleus (GO:0005634)
THO complex [is_a relation] is_a  nuclear part (GO:0044428)
THO complex [is_a relation] is_a  protein complex (GO:0043234)
Children of THO complex (GO:0000347)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nucleoplasmic THO complex (GO:0000446) [is_a relation] is_a  THO complex
THO complex part of transcription export complex (GO:0000445) [is_a relation] is_a  THO complex
None.