Term Information [More information on nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]

Accession
GO:0000184
Name
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Ontology
biological_process
Synonyms
mRNA breakdown, nonsense-mediated decay, mRNA catabolic process, nonsense-mediated, mRNA catabolism, nonsense-mediated, mRNA degradation, nonsense-mediated decay, nonsense-mediated mRNA decay, nuclear mRNA catabolic process, nonsense-mediated decay
Definition
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. Source: GOC:krc, PMID:10025395, GOC:ma
Comment
None
History
See term history for GO:0000184 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0000184 from QuickGO

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Ancestors of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) biological_process (GO:0008150)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) cellular process (GO:0009987)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) metabolic process (GO:0008152)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) cellular metabolic process (GO:0044237)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) nitrogen compound metabolic process (GO:0006807)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) organic substance metabolic process (GO:0071704)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) catabolic process (GO:0009056)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) cellular aromatic compound metabolic process (GO:0006725)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) cellular nitrogen compound metabolic process (GO:0034641)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) heterocycle metabolic process (GO:0046483)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) organic cyclic compound metabolic process (GO:1901360)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) primary metabolic process (GO:0044238)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) cellular catabolic process (GO:0044248)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) macromolecule metabolic process (GO:0043170)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) nucleobase-containing compound metabolic process (GO:0006139)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) organic substance catabolic process (GO:1901575)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) aromatic compound catabolic process (GO:0019439)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) cellular macromolecule metabolic process (GO:0044260)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) cellular nitrogen compound catabolic process (GO:0044270)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) heterocycle catabolic process (GO:0046700)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) macromolecule catabolic process (GO:0009057)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) nucleic acid metabolic process (GO:0090304)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) organic cyclic compound catabolic process (GO:1901361)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) cellular macromolecule catabolic process (GO:0044265)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) nucleobase-containing compound catabolic process (GO:0034655)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) RNA metabolic process (GO:0016070)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) mRNA metabolic process (GO:0016071)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) RNA catabolic process (GO:0006401)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Inferred is_a relation] is_a (inferred) mRNA catabolic process (GO:0006402)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [is_a relation] is_a  nuclear-transcribed mRNA catabolic process (GO:0000956)
Children of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:2000623) [negatively_regulates relation] negatively_regulates  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay (GO:0070478) [is_a relation] is_a  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay (GO:0070479) [is_a relation] is_a  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:2000624) [positively_regulates relation] positively_regulates  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:2000622) [regulates relation] regulates  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay