Term Information [More information on transcription regulatory region DNA binding]

Accession
GO:0044212
Name
transcription regulatory region DNA binding
Ontology
molecular_function
Synonyms
None
Definition
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors. Source: GOC:txnOH, SO:0005836, GOC:jl
Comment
The word "promoter" is used variously in the literature to describe the core promoter specifically or the entire proximal regulatory region (excluding any distal enhancers) including both the core promoter and the upstream region where activating transcription factors such as Gal4 in S. cerevisiae or catabolite activator protein (CAP) in E. coli bind. To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" in order to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind, and "enhancer" regions which are typically more distal from the core promoter. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription. ANNOTATION NOTE: Regarding annotation to "transcription regulatory region DNA binding" (GO:0044212) and any of its is_a children, note that annotation to these terms specifies DNA binding only without any statement about transcription factor activity. To make an annotation about a function of transcription factor activity, consider "sequence-specific DNA binding transcription factor activity" (GO:0003700) or its is_a children which have has_part relationships to the appropriate kind of "transcription regulatory region DNA binding".
History
See term history for GO:0044212 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0044212 from QuickGO

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Ancestors of transcription regulatory region DNA binding (GO:0044212)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transcription regulatory region DNA binding [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
transcription regulatory region DNA binding [Inferred is_a relation] is_a (inferred) binding (GO:0005488)
transcription regulatory region DNA binding [Inferred is_a relation] is_a (inferred) heterocyclic compound binding (GO:1901363)
transcription regulatory region DNA binding [Inferred is_a relation] is_a (inferred) organic cyclic compound binding (GO:0097159)
transcription regulatory region DNA binding [Inferred is_a relation] is_a (inferred) nucleic acid binding (GO:0003676)
transcription regulatory region DNA binding [Inferred is_a relation] is_a (inferred) DNA binding (GO:0003677)
transcription regulatory region DNA binding [Inferred is_a relation] is_a (inferred) regulatory region nucleic acid binding (GO:0001067)
transcription regulatory region DNA binding [is_a relation] is_a  regulatory region DNA binding (GO:0000975)
Children of transcription regulatory region DNA binding (GO:0044212)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
bacterial-type RNA polymerase regulatory region DNA binding (GO:0001017) [is_a relation] is_a  transcription regulatory region DNA binding
cAMP response element binding (GO:0035497) [is_a relation] is_a  transcription regulatory region DNA binding
carbohydrate response element binding (GO:0035538) [is_a relation] is_a  transcription regulatory region DNA binding
core promoter binding (GO:0001047) [is_a relation] is_a  transcription regulatory region DNA binding
core promoter proximal region DNA binding (GO:0001159) [is_a relation] is_a  transcription regulatory region DNA binding
E-box binding (GO:0070888) [is_a relation] is_a  transcription regulatory region DNA binding
enhancer binding (GO:0035326) [is_a relation] is_a  transcription regulatory region DNA binding
estrogen response element binding (GO:0034056) [is_a relation] is_a  transcription regulatory region DNA binding
intronic transcription regulatory region DNA binding (GO:0044213) [is_a relation] is_a  transcription regulatory region DNA binding
juvenile hormone response element binding (GO:0070594) [is_a relation] is_a  transcription regulatory region DNA binding
mitochondrial heavy strand promoter anti-sense binding (GO:0070362) [is_a relation] is_a  transcription regulatory region DNA binding
mitochondrial heavy strand promoter sense binding (GO:0070364) [is_a relation] is_a  transcription regulatory region DNA binding
mitochondrial light strand promoter anti-sense binding (GO:0070361) [is_a relation] is_a  transcription regulatory region DNA binding
mitochondrial light strand promoter sense binding (GO:0070363) [is_a relation] is_a  transcription regulatory region DNA binding
mitochondrial RNA polymerase regulatory region DNA binding (GO:0001018) [is_a relation] is_a  transcription regulatory region DNA binding
N-box binding (GO:0071820) [is_a relation] is_a  transcription regulatory region DNA binding
negative regulation of transcription regulatory region DNA binding (GO:2000678) [negatively_regulates relation] negatively_regulates  transcription regulatory region DNA binding
plastid RNA polymerase regulatory region DNA binding (GO:0001019) [is_a relation] is_a  transcription regulatory region DNA binding
positive regulation of transcription regulatory region DNA binding (GO:2000679) [positively_regulates relation] positively_regulates  transcription regulatory region DNA binding
purine-rich negative regulatory element binding (GO:0032422) [is_a relation] is_a  transcription regulatory region DNA binding
regulation of transcription regulatory region DNA binding (GO:2000677) [regulates relation] regulates  transcription regulatory region DNA binding
retinoic acid-responsive element binding (GO:0044323) [is_a relation] is_a  transcription regulatory region DNA binding
RNA polymerase I regulatory region DNA binding (GO:0001013) [is_a relation] is_a  transcription regulatory region DNA binding
RNA polymerase II regulatory region DNA binding (GO:0001012) [is_a relation] is_a  transcription regulatory region DNA binding
RNA polymerase III regulatory region DNA binding (GO:0001016) [is_a relation] is_a  transcription regulatory region DNA binding
serum response element binding (GO:0010736) [is_a relation] is_a  transcription regulatory region DNA binding
sterol response element binding (GO:0032810) [is_a relation] is_a  transcription regulatory region DNA binding
transcription regulatory region sequence-specific DNA binding (GO:0000976) [is_a relation] is_a  transcription regulatory region DNA binding
transcription termination site DNA binding (GO:0001160) [is_a relation] is_a  transcription regulatory region DNA binding
vitamin D response element binding (GO:0070644) [is_a relation] is_a  transcription regulatory region DNA binding
None.